The safety risks and challenges faced by urban development in terms of "severe fire", "small fire causes great casualties", potential dangers of old buildings, new business risks, etc. were elaborated. The role of scientific and technological innovation in urban fire safety was expounded from the aspects of assisting smart cities, innovating prevention and control technologies, accelerating the tackling of difficult problems, and focusing on emergency rescue. Prospect of innovation and integration development of urban fire safety technology with the help of taking multiple measures to strengthen top- level planning and design, focus on breaking through key and core technologies, and make overall layout for the construction of fire technology innovation platform were put forward.