Abstract: In order to reduce the occurrence of liquid ammonia leakage accident, this paper constructs the index system of influencing factors of liquid ammonia leakage accident from four aspects of man,machine,enviroment and management. The centrality and cause degree of 15 influencing factors were calculated by using Decision Laboratory Analysis (DEMATEL), and the key influencing factors and the causal attributes of influencing factors were determined. Combined with the Interpretative Structure Model (ISM), the hierarchical structure model of influencing factors of liquid ammonia leakage accident is constructed, and the internal relationship among the influencing factors is determined. Taking a dairy enterprise as an example, the effectiveness of DEMATEL-ISM model is verified. The results show that the DEMATEL-ISM model can directly reflect the mutual influence relationship between the accident influencing factors, and determine the key influencing factors of liquid ammonia leakage accident, so as to provide a reliable basis for enterprise safety decision-making.

Key words: liquid ammonia leakage, DEMATEL, centrality, influencing factors